Should We Consider Primary Hyperparatyroidism in Multiple Myeloma Cases with Hypercalcemia

Should We Consider another Booster Dose of Measles Vaccine?

Background: To date, 36 years has passed since the beginning of measles vaccination; the disease is still circulating around the world, threatening lives of human beings especially in developing countries.  In recent years, we have confronted measles in previously vaccinated adults from all over the country. Objective: To find out if there is a need for changing our routine measles vaccination ...

Erythema nodosum :what should we consider about it?

Multiple Myeloma and Hypercalcemia ?

We presenta case ofmultiplemyeloma with high valuesfor total calcium.The case discussion focuses on the role of the laboratoryindiagnosisand monitoring ofmultiplemyeloma and on the causes ofthe associated hypercalcemia.We present evidence for calcium binding to the paraprotein as a cause for the “hypercalcemia” inthiscaseand we document a difference inthe resultsfortotalcalcium among various me...

Multiple myeloma/hypercalcemia

Multiple myeloma, a cancer of plasma cells, is associated with excessive tumor-induced, osteoclast-mediated bone destruction. Hypercalcemia remains the most frequent metabolic complication of myeloma in patients, and excessive osteolysis plays a major contributory role in its pathogenesis. The clinical presentation of hypercalcemia in patients varies depending on the level of ionized calcium; i...

Acute Pancreatitis in a Case of Multiple Myeloma with Hypercalcemia

A patient with hypercalcemia and newly diagnosed multiple myeloma developed acute pancreatitis. Other etiologic factors for pancreatitis were excluded. Hypercalcemia secondary to hyperparathyroidism is associated with acute pancreatitis. In English literature, only one other case has been published where the hypercalcemia of multiple myeloma may have caused pancreatitis. Pancreatitis should be ...